Comprehensive analysis of the life quality in patients with senile asthnia syndrome in combination
with atrial fibrillation and iron deficiency anemia 

Larisa F. Burmistrova, Candidate of medical sciences, associate professor, acting head of the sub-department of polyclinic therapy and mobilization training in healthcare, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: lamax-69@mail.ru
Mikhail V. Petrov, Senior lecturer of the sub-department of polyclinic therapy and mobilization training in healthcare, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: mikh.petrov1@yandex.ru
Inessa Ya. Moiseeva, Doctor of medical sciences, professor, head of the sub-department of general and clinical pharmacology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: moiseeva_pharm@mail.ru
Irina A. Komissarenko, Doctor of medical sciences, professor of the sub-department of therapy and preventive medicine, Moscow State Medical and Dental University named after A.I. Evdokimov (4 Dolgorukovskaya street, Moscow, Russia), E-mail: komisarenko@mail.ru
Ol'ga N. Sisina, Candidate of medical sciences, associate professor of the sub-department of polyclinic therapy and mobilization training in healthcare, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: olganikolaevna58@bk.ru 

Background. Assessment of the life quality in patients with atrial fibrillation in combination with iron deficiency anemia and senile asthenia (SA) is insufficiently presented in the modern literature. At the same time, it is the quality of life that is the final goal of any treatment method. Determining such a relationship in clinical practice is an urgent problem. The purpose of the research was to study the level of the life quality in patients with frailty syndrome in combination with atrial fibrillation (AF) and iron deficiency anemia (IDA). Materials and methods. The main group included 48 patients with SA syndrome in combination with AF and IDA, 2 control groups were also formed (1 – 39 patients with SA and AF, 2 – 41 patients with SA syndrome without pronounced comorbid pathologies), in all groups, QL indicators were determined according to the validated SF-36 questionnaire. Results. A significant difference in the level of the life quality between the main group and control group 1 was obtained according to the following indicators: PF – 41.1 ± 22.3 and 49.8 ± 23.1, RP – 40.2 ± 23.5 and 48.5 ± 20, 9, GH – 41.4 ± 24.8 and 48.4 ± 22.1, VT – 42.1 ± 26.7 and 49.9 ± 23.5, RE – 41.1 ± 18.8 and 49, 3 ± 19.3. At the same time, patients of the main group had a lower quality of life compared to the 2nd control group on absolutely all scales: PF – 41.1 ± 22.3 and 62.5 ± 24.6, RP – 40.2 ± 23.5 and 57.5 ± 22.1, GH – 41.4 ± 24.8 and 55.7 ± 20.8, VT – 42.1 ± 26.7 and 57.4 ± 25.2, SF – 43.5 ± 22.2 and 55.4 ± 26.8, MH – 46.8 ± 19.5 and 57.5 ± 25.9, RE – 41.1 ± 18.8 and 58.4 ± 26.6, BP – 43.6 ± 20.3 and 63.2 ± 25.6. Conclusions. The influence of IDA on a number of assessment scales of the life quality (PF, RP, GH, VT, RE) is determined, which reflect both the physical and psychosocial aspects of life. As a screening based on the validated SF-36 questionnaire, at the first stage it is necessary to determine the indicators PF, RP, GH, VT, RE as the most reliable reflection of the effect of IDA on the life quality. 

quality of life, atrial fibrillation, iron deficiency anemia 

Burmistrova L.F., Petrov M.V., Moiseeva I.Ya., Komissarenko I.A., Sisina O.N. Comprehensive analysis of the life quality in patients with senile asthnia syndrome in combination with atrial fibrillation and iron deficiency anemia. Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2023;(4):137–144. (In Russ.). doi: 10.21685/2072-3032-2023-4-14